America: Gene therapy cures deafness in a mouse

<p style=";text-align:left;direction:ltr">ArabiaWeather.com – In search of a radical treatment for deafness, a genetic treatment for deafness came to light in a laboratory at Boston Children’s Hospital, which research director Jeff Holt said opens the door to treating every child who loses hearing due to a genetic defect if everything goes as it should. It is planned.</p><p style=";text-align:left;direction:ltr"></p><p style=";text-align:left;direction:ltr"> Holt added that his fellow researchers are tackling this problem upstream, using genetically modified viruses to repair faulty genes that make up the inner ear.</p><p style=";text-align:left;direction:ltr"></p><p style=";text-align:left;direction:ltr"> More precisely, this treatment is based on taking a viral vector and removing the viral genes so that they do not infect anyone with the disease, and replacing them with the correct DNA infiltration of the TMC1 gene.</p><p style=";text-align:left;direction:ltr"></p><p style=";text-align:left;direction:ltr"> TMC1 is of vital importance to the sense of hearing as it is responsible for decoding proteins that convert sounds into electrical signals that the brain can understand.</p><p style=";text-align:left;direction:ltr"></p><p style=";text-align:left;direction:ltr"> Holt and his team tested their treatment program on two types of deaf mice that had a mutation of the TMC1 gene similar to what happens in humans, and the team used a genetically modified virus, &quot;AV1&quot;, to deliver the correct gene to the inner ear of two deaf mouse models.</p><p style=";text-align:left;direction:ltr"></p><p style=";text-align:left;direction:ltr"> See also:</p><p style=";text-align:left;direction:ltr"> <a href="http://jo.arabiaweather.com/content/%D9%85%D9%84%D9%83%D8%A9-%D8%A7%D9%8... queen..the strangest insect you may ever see</a></p><p style=";text-align:left;direction:ltr"> <a href="http://jo.arabiaweather.com/content/%D9%84%D9%88%D9%83%D8%B3%D9%88%D9%85... Find the largest conch in the world</a></p><p style=";text-align:left;direction:ltr"> <a href="http://jo.arabiaweather.com/content/%D8%A8%D8%A7%D9%84%D8%B5%D9%88%D8%B1... Sea creatures that will surprise you with their beauty</a></p><p style=";text-align:left;direction:ltr"></p>